Singh B (2013) Evolution of a revolution, an autobiographical account on formulation by design.

The Pharma Review 11:36–42

Singh B (2014) Quality by design (QbD) for holistic pharma excellence and regulatory compliance.

Pharma Times 46:26–33

Singh G, Pai RS (2015) Trans-resveratrol self-nano-emulsifying drug delivery system (SNEDDS)

with enhanced bioavailability potential: optimization, pharmacokinetics and in situ single pass

intestinal perfusion (SPIP) studies. Drug Deliv 22(4):522–530

Singh B, Dahiya M, Saharan V, Ahuja N (2005a) Optimizing drug delivery systems using

systematic “design of experiments.” Part II: retrospect and prospects. Crit Rev Ther Drug

Carrier Syst 22(3):215–294

Singh B, Kumar R, Ahuja N (2005b) Optimizing drug delivery systems using systematic “design of

experiments.” Part I: fundamental aspects. Crit Rev Ther Drug Carrier Syst 22(1):27–105

Singh B, Bandopadhyay S, Kapil R, Singh R, Katare OP (2009a) Self-emulsifying drug delivery

systems (SEDDS): formulation development, characterization, and applications. Crit Rev Ther

Drug Carrier Syst 26(5):427–451

Singh B, Pahuja S, Kapil R, Ahuja N (2009b) Formulation development of oral controlled release

tablets of hydralazine: optimization of drug release and bioadhesive characteristics. Acta

Pharma 59(1):1–13

Singh B, Bhatowa R, Tripathi CB, Kapil R (2011a) Developing micro-/nanoparticulate drug

delivery systems using “design of experiments”. Int J Pharm Investig 1(2):75–87

Singh B, Khurana L, Bandyopadhyay S, Kapil R, Katare OP (2011b) Development of optimized

self-nano-emulsifying drug delivery systems (SNEDDS) of carvedilol with enhanced bioavail-

ability potential. Drug Deliv 18(8):599–512

Singh B, Kapil R, Nandi M, Ahuja N (2011c) Developing oral drug delivery systems using

formulation by design: vital precepts, retrospect and prospects. Expert Opin Drug Deliv

8(10):1341–1360

Singh B, Garg B, Chaturvedi SC, Arora S, Mandsaurwale R, Kapil R et al (2012) Formulation

development of gastroretentive tablets of lamivudine using the floating-bioadhesive potential of

optimized polymer blends. J Pharm Pharmacol 64(5):654–669

Singh B, Raza K, Beg S (2013) Developing “optimized” drug products employing “designed”

experiments. Chemical Industry Digest (12):70–76

Singh B, Beg S, Khurana RK, Sandhu PS, Kaur R, Katare OP (2014) Recent advances in self-

emulsifying drug delivery systems (SEDDS). Crit Rev Ther Drug Carrier Syst 31(2):121–185

Singh B, Khurana RK, Lohan S, Sandhu PS, Beg S, Anuja N (2015) Developing optimized

nanopharmaceuticals employing rational use of systematic multivariate techniques. In:

Singh B, Singh KK, Rekhi GS (eds) NanoBioMedicine, vol 2. Studium Press LLC, USA, pp

251–303

Singh B, Khurana RK, Garg B, Saini S, Kaur R (2017a) Stimuli-responsive systems with diverse

drug delivery and biomedical applications: recent updates and mechanistic pathways. Crit Rev

Ther Drug Carrier Syst 34(3):209–255

Singh B, Saini S, Lohan S, Beg S (2017b) Systematic development of nanocarriers employing

quality by design paradigms. In: Mishra V, Kesharwani P, Amin MCIM, Iyer A (eds)

Nanotechnology-based approaches for targeting and delivery of drugs and genes. Academic

Press, USA, pp 110–148

Singh B, Garg B, Sandhu PS, Kaur R, Saini S (2018a) Systematic optimization of pharmaceutical

products and processes using modern approaches. In: Jain NK (ed) Pharmaceutical product

development. CBS Publishers, India, pp 383–435

Singh C, Kaur R, Kaur R, Bahl R, Singh B (2018b) Multi-dimensional approaches for targeted drug

delivery

using

nanostructured

systems.

In:

Singh

B,

Kanwar

JR,

Garg

S

(eds)

NanoBioEngineering. CRC Press, USA, pp 123–144

Sun YP, Fu K, Lin Y, Huang W (2002) Functionalized carbon nanotubes: properties and

applications. Acc Chem Res 35(12):1096–1104

Sylvester B, Porfire A, Achim M, Rus L, Tomuţă I (2018) A step forward towards the development

of stable freeze-dried liposomes: a quality by design approach (QbD). Drug Devel Ind Pharm

44(3):385–397

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